Our People

So here we are!

  1. Archana Samal (PhD student – UGC-SRF)
  2. Surajit Gandhi (PhD student – UGC-SRF)
  3. Somanath Baral (PhD student – Project JRF)
  4. Ketul Saharan (PhD student – UGC-SRF)
  5. Ruchir Chandrakant Bobde (PhD student – SRF)
  6. Shaikh Nausad Hossain (Post-doctoral fellow – CSIR-SRA)
  7. Aritreyee Datta (Post-doctoral fellow – DBT-RA)
  8. Chinmayee Mohapatra (Woman Scientist – DST WOS-A)
  9. Swabhiman Sahu (XRD Facility in-charge)
  10. Manoj Kumar Barik (Laboratory technician)
  11. Dileep Vasudevan (Lab head – Scientist D)

Group-pic - 27Apr2022

Upper Row: Chinmayee, Nausad & Aritreyee

Middle Row:  Ruchir, Ketul, Somanath, Surajit & Archana

Lower Row: Swabhiman, Manoj & Dileep.

Interestingly, most of us didn’t have any plan to do what we are doing now. We are a diverse lot (or a mixed bag) with varying interests and still, we are in a group, cutting-the-edges, Err! we mean… doing cutting-edge science projects. 😉 We strongly believe in “Unity in Diversity” and we come from different parts of the country – Haryana, Maharashtra, Odisha, West Bengal, Tamil Nadu, and Kerala. People form our strength and our progress lies in staying happy.


Archana-for-website

Archana Samal

  • BSc Honors (Botany) Honors, Shailabala Women’s College, Cuttack, 2016.
  • MSc (Life Sciences), Central University of Punjab, Bathinda, 2018.
  • Project JRF at Utkal University (Feb 2019 – Nov 2019).
  • Joined ILS as a PhD scholar in March 2020.
  • Her PhD is registered with RCB, Faridabad.
  • Current research interest: Chromatin structural biology

Archana joined our group as a PhD student with UGC JRF. Before joining us, she has worked as a JRF in a Govt. of Odisha DST-funded project with Prof. J. Dandapat at Utkal University, Bhubaneswar. She has learnt our kind of experiments with help from senior students in the lab. Her PhD projects are around the theme of chromatin and infectious disease structural biology. She will take over the spill-over projects from Manas. She has been making good progress with all her projects and has been part of our ESRF (France) remote data collection team twice. She has started getting crystals for two of her projects. Her PhD is registered with Regional Centre for Biotechnology (RCB), Faridabad.

Publication:

  • Ruchir C. Bobde*, Ketul Saharan*, Somanath Baral, Surajit Gandhi, Archana Samal, Rajivgandhi Sundaram, Ashish Kumar, Ajit Kumar Singh, Aritreyee Datta, Dileep Vasudevan. 2021In vitro characterization of histone chaperones using analytical, pull-down and chaperoning assays. Journal of Visualized Experiments [JoVE] 63218.

image avi

Surajit Gandhi

  • BSc (Zoology), Banwarilal Bhalotia College, Asansol, 2016.
  • MSc (Zoology), University of Burdwan, Purba Bardhaman, 2018.
  • Joined ILS as a PhD scholar in February 2020.
  • His PhD is registered with RCB, Faridabad.
  • Current research interest: Chromatin & infectious disease structural biology

Surajit joined our group as a PhD student with UGC-JRF. He has gotten familiarized with the experiments carried out in a structural biology laboratory. His PhD projects are in the interface of chromatin and infectious disease structural biology. He is very agile and keeps himself busy in lab all the time. He has been a great help in tying up the loose ends from the projects Rajiv have been doing with us. He has completed two crystal structures and has more crystals waiting. He also took part in our ESRF remote data collection exercise. His PhD is registered with Regional Centre for Biotechnology (RCB), Faridabad.

Publication:

  • Ruchir C. Bobde*, Ketul Saharan*, Somanath Baral, Surajit Gandhi, Archana Samal, Rajivgandhi Sundaram, Ashish Kumar, Ajit Kumar Singh, Aritreyee Datta, Dileep Vasudevan. 2021In vitro characterization of histone chaperones using analytical, pull-down and chaperoning assays. Journal of Visualized Experiments [JoVE] 63218.

image

Somanath Baral

  • BSc Honors (Botany), Utkal University, Bhubaneswar, 2015.
  • MSc (Botany), Berhampur University, Berhampur, 2017.
  • MPhil (Botany), Berhampur University, Berhampur, 2019.
  • Project JRF, IIT Kharagpur, May 2019 – December 2019.
  • Joined ILS as a Project JRF in January 2020.
  • His PhD is registered with KIIT University, Bhubaneswar.
  • Current research interests: Chromatin & nucleoplasmins

Somanath joined our group as a JRF in a SERB-funded project in January 2020. Before joining ILS, he was working as a project JRF at the Centre for Bioenergy and Renewables, IIT Kharagpur. With us, he is working on a project dealing with plant chromatin and the associated histone chaperones, for structural studies. It is a continuation of Ajit’s work. He works along with Ketul for some part of his work. He too took part in our ESRF (France) remote data collection twice. His PhD is registered with KIIT University, Bhubaneswar.

Publication:

  • Ruchir C. Bobde*, Ketul Saharan*, Somanath Baral, Surajit Gandhi, Archana Samal, Rajivgandhi Sundaram, Ashish Kumar, Ajit Kumar Singh, Aritreyee Datta, Dileep Vasudevan. 2021In vitro characterization of histone chaperones using analytical, pull-down and chaperoning assays. Journal of Visualized Experiments [JoVE] 63218.
  • Ajit Kumar Singh*, Ketul Saharan*, Somanath Baral, Sheng Luan, Dileep Vasudevan.  2022. Crystal packing reveals rapamycin-mediated homodimerization of an FK506-binding domain. International Journal of Biological Macromolecules 206: 670-80.
  • Ajit Kumar Singh*, Ketul Saharan*, Somanath Baral, Dileep Vasudevan. 2022. The plant nucleoplasmin AtFKBP43 needs its extended arms for histone interaction. bioRxiv DOI: 10.1101/2022.04.25.489347.

DSC_3956

Ketul Saharan

  • BSc (Biotechnology), Government National College, Sirsa, 2014.
  • MSc (Botany), Kurukshetra University, Kurukshetra, 2016.
  • JRF at School of Life Sciences, JNU, New Delhi, Aug 2017 – Feb 2019.
  • Joined ILS as a PhD scholar in March 2019.
  • His PhD is registered with RCB, Faridabad.
  • Current research interest: Chromatin, histone chaperones & HDACs

Ketul joined our group as a PhD student with UGC-JRF. Before joining our group at ILS, he was a Junior Research Fellow in the structural biology laboratory at the School of Life Sciences, JNU, New Delhi. He has prior experience with molecular biology, protein chemistry, and SAXS experiments. In the lab, you will find him busy all the time, except during his afternoon ‘power nap’ time. He has completed the crystal structure for two proteins from his PhD project and has accumulated plenty of biophysical data. He has gained experience collecting diffraction data from RRCAT, Indore and remote data collection at ESRF (France). His PhD work is around the broad theme of chromatin, histone chaperones, and histone deacetylases. He is a hard worker with no compromise. He already has two co-first author publications with us and another co-first author manuscript from his work is out in BioRxiv pre-print journal. His PhD is registered with Regional Centre for Biotechnology (RCB), Faridabad.

Publication:

  • Ruchir C. Bobde*, Ketul Saharan*, Somanath Baral, Surajit Gandhi, Archana Samal, Rajivgandhi Sundaram, Ashish Kumar, Ajit Kumar Singh, Aritreyee Datta, Dileep Vasudevan. 2021In vitro characterization of histone chaperones using analytical, pull-down and chaperoning assays. Journal of Visualized Experiments [JoVE] 63218. [*Co-first author]
  • Ajit Kumar Singh*, Ketul Saharan*, Somanath Baral, Sheng Luan, Dileep Vasudevan.  2022. Crystal packing reveals rapamycin-mediated homodimerization of an FK506-binding domain. International Journal of Biological Macromolecules 206: 670-80. [*Co-first author]
  • Ajit Kumar Singh*, Ketul Saharan*, Somanath Baral, Dileep Vasudevan. 2022. The plant nucleoplasmin AtFKBP43 needs its extended arms for histone interaction. bioRxiv DOI: 10.1101/2022.04.25.489347. [*Co-first author]

DSC_3960

Ruchir Chandrakant Bobde

  • BSc (Chemistry, Microbiology, Biotechnology), RTM Nagpur University, Nagpur, 2013.
  • MSc (Biotechnology), RTM Nagpur University, Nagpur, 2016.
  • Trainee at ACTREC, Navi Mumbai, Jan 2016 – Mar 2016.
  • Project staff at ICAR-CICR, Nagpur, Oct 2016 – Jan 2017.
  • Joined ILS as a PhD scholar in January 2017.
  • His PhD is registered with RCB, Faridabad.
  • Current research interest: Chromatin & HDACs

Ruchir joined as a PhD student with an institutional fellowship. He has had some prior research experience in the broad areas of molecular and cell biology. He has been a quick learner and an amicable social-being. He has gotten high-resolution data for two of the HDAC proteins from his thesis work and two bacterial proteins from a collaborative project. The structures have all been solved and he is busy with some additional biophysical studies on the proteins. His joint project with Ashish has taken the shape of a heavy manuscript and is currently under review! He has gained experience collecting X-ray diffraction data from RRCAT, Indore, and SAXS data from ESRF (France). His PhD is registered with Regional Centre for Biotechnology (RCB), Faridabad.

Publications:

  • Ashish Kumar, Ajit K. Singh, Ruchir C. Bobde, Dileep Vasudevan. 2019. Structural characterization of Arabidopsis thaliana NAP1-Related Protein 2 (AtNRP2) and comparison with its homolog AtNRP1. Molecules 24(12) pii: E2258.
  • Ruchir C. Bobde*, Ketul Saharan*, Somanath Baral, Surajit Gandhi, Archana Samal, Rajivgandhi Sundaram, Ashish Kumar, Ajit Kumar Singh, Aritreyee Datta, Dileep Vasudevan. 2021In vitro characterization of histone chaperones using analytical, pull-down and chaperoning assays. Journal of Visualized Experiments [JoVE] 63218.

DSC_3967

Shaikh Nausad Hossain

  • BSc (Biotechnology), Bangalore University, 2005.
  • Diploma (Genetic Engineering), JIVAS, Bangalore, 2005.
  • Project JRF at PGIMER, Chandigarh, 2005-2006.
  • MSc (Molecular Biology), University of Queensland, Australia, 2008.
  • Research Assistant, University of Queensland, Australia, 2008-2009.
  • PhD (Structural Biology), University of Queensland, Australia, 2013.
  • Post-doctoral fellow at Okinawa Institute of Science and Technology (OIST), Japan, 2013-2016.
  • Visiting post-doctoral fellow at NISER, Bhubaneswar, 2017-2018.
  • Joined ILS as a post-doc in July 2018 and continuing as a CSIR- Senior Research Associate from December 2019.
  • Current research interest: Infectious disease structural biology

Nausad joined our group in July 2018. His PhD is from the University of Queensland, Australia under the guidance of Prof. Glenn F. King and the co-guidance of Prof. Brett Collins. After his PhD, he moved Okinawa, Japan for a post-doctoral position at the Okinawa Institute of Science and Technology (OIST) in the Trans-Membrane Trafficking Unit under Prof. Fadel Samatey. He has gained extensive experience in protein crystallography, NMR, and protein biophysics. After a brief stay at NISER, Bhubaneswar as a visiting post-doctoral fellow, Nausad moved to ILS. He was initially an institutional post-doctoral fellow and later he got his own fellowship – CSIR-SRA. With us, Nausad works on projects dealing with infectious disease structural biology. In addition to his own project, he has been working on WSSV proteins and have gotten two manuscripts on the theme.

Publication:

  • Vipul Panchal*, Sushil Kumar*, Shaikh Nausad Hossain#, Dileep Vasudevan#2020. Structure analysis of thymidylate synthase from white spot syndrome virus reveals WSSV-specific structural elements.  International Journal of Biological Macromolecules S0141-8130(20)34996-5. [#Co-corresponding author]
  • Aritreyee Datta*, Shaikh Nausad Hossain*, Chinmayee Mohapatra#, Dileep Vasudevan# 2022.  Structural insights into proteins from White spot syndrome virus: perspectives on structure-based anti-viral strategies. Reviews in Aquaculture 2022: 1-12. [* Co-first author]

IMG_0829.JPG

Aritreyee Datta

  • BSc (Biotechnology), Bangalore University, Bangalore, 2007.
  • MSc (Biotechnology), KIIT University, Bhubaneswar, 2010.
  • SRF in Bose Institute, Kolkata, 2012-2017.
  • PhD (Biotechnology), University of Kolkata, Kolkata, 2017.
  • Institutional post-doc in our group from August 2017 to April 2018.
  • SERB N-PDF from April 2018 to April 2020.
  • Continuing as DBT-RA from October 2020.
  • Current research interest: HDACs from the malarial parasite

Aritreyee joined us while waiting for her PhD defence and later got selected for SERB N-PDF. Currently, she is continuing with a DBT-RA fellowship. Her PhD is from the University of Kolkata. Her thesis work was carried out under the guidance of Dr. Anirban Bhunia (Bose Institute, Kolkata) in the area of protein NMR. Her skillset is in NMR, spectroscopy, microscopy, and protein interaction studies. She has had a very productive (read it as publication-rich) PhD and she indeed brought in that ‘much-needed’ flavour to our group as well. Her hands are now well set for crystallography experiments. She has amazing writing and editing skills! Our in-house editor she is! The below publications would not have seen the light without her contribution!

Publication:

  • Ajit K. Singh, Aritreyee Datta, Jobichen Chacko, Sheng Luan, Dileep Vasudevan. 2020. AtFKBP53: a chimeric histone chaperone with functional nucleoplasmin and PPIase domains. Nucleic Acids Research 48(3): 1531–1550.
  • Ruchir C. Bobde*, Ketul Saharan*, Somanath Baral, Surajit Gandhi, Archana Samal, Rajivgandhi Sundaram, Ashish Kumar, Ajit Kumar Singh, Aritreyee Datta, Dileep Vasudevan. 2021In vitro characterization of histone chaperones using analytical, pull-down and chaperoning assays. Journal of Visualized Experiments [JoVE] 63218.
  • Aritreyee Datta*, Shaikh Nausad Hossain*, Chinmayee Mohapatra#, Dileep Vasudevan# 2022.  Structural insights into proteins from White spot syndrome virus: perspectives on structure-based anti-viral strategies. Reviews in Aquaculture 2022: 1-12.

Chinmayee

Chinmayee Mohapatra

  • BSc Honors (Botany), Utkal University, Bhubaneswar, 2005.
  • MSc (Biotechnology), Utkal University, Bhubaneswar, 2007.
  • BCIL trainee in Imgenex India Pvt. Ltd., Bhubaneswar, 2007-2008.
  • JRF/SRF in CIFA, Bhubaneswar, 2008-2014.
  • Ph.D. (Cell & Molecular Biology), Utkal University, Bhubaneswar, 2014.
  • Post-doc in our group at ILS from April 2014-June 2018 as DBT-RA and then SERB N-PDF.
  • Guest Faculty at Ravenshaw University, Cuttack and BJB College, Bhubaneswar (2018-2019).
  • Joined back in ILS as a joint post-doc from Dec 2019.
  • Current research interest: Clp machinery chaperones, Viral NSPs and inhibitors

Chinmayee first came to ILS for her Utkal University PhD coursework. Later she joined our bandwagon with her own project funded by DBT (DBT-RA scheme). She then got her funding changed to SERB N-PDF. Her PhD work around the theme of fish spermatogonial stem cells was carried out in CIFA (Bhubaneswar) under the guidance of Dr. Hirak K. Barman. Her skillset has been molecular and cell biology. In our group, she learned the nitty-gritty of protein chemistry and protein crystallization as well. She works on plant and mycobacterial chaperones in our group. The first research manuscript from our group is hers, along with Manas. She has gained experience collecting X-ray data from RRCAT (India), ESRF (France) as well as in-house machines. At ESRF (France), she carried out SAXS data collection for the lab. In between, she worked as a guest faculty at Ravenshaw University, Cuttack, and as a visiting faculty at BJB College, Bhubaneswar. She then moved back to ILS as a project post-doctoral fellow. More recently, she has moved into the WOS-A Woman Scientist scheme from DST and is continuing to work with us.

Publications:

  • Chinmayee Mohapatra*, Manas K. Jagdev*, Dileep Vasudevan. 2017. Crystal structures reveal N-terminal Domain of Arabidopsis thaliana ClpD to be highly divergent from that of ClpC1. Scientific Reports 7: 44366.
  • Dileep Vasudevan, Manas K. Jagdev, Chinmayee Mohapatra2017. Structural basis of mycobacterial inhibition by natural products targeting ClpC1. XXIV IUCr Congress Abstract. Acta Crystallographica A. A73 A2, C228.
  • Chinmayee Mohapatra, Manas K. Jagdev, Dileep Vasudevan. 2017. Arabidopsis ClpD N-terminal domain is highly divergent from ClpC1. XXIV IUCr Congress Abstract. Acta Crystallographica A. A73 A2, C246.
  • Aritreyee Datta*, Shaikh Nausad Hossain*, Chinmayee Mohapatra#, Dileep Vasudevan# 2022.  Structural insights into proteins from White spot syndrome virus: perspectives on structure-based anti-viral strategies. Reviews in Aquaculture 2022: 1-12. [# Co-corresponding author]

Swabhiman

Swabhiman Sahu

  • PGDCA, Softech, Cuttack, 2017.
  • BSc Honors (Zoology), Ravenshaw University, Cuttack, 2018.
  • MSc (Life Sciences), Jawaharlal Nehru University, New Delhi, 2020.
  • Joined ILS as the X-ray Diffraction Facility In-Charge from April 2022.

Swabhiman has a keen interest in Structural Biology and has carried out his MSc dissertation project in JNU, New Delhi under the guidance of Dr. Samudrala Gourinath in the area of protein crystallography. Along with his responsibility as an in-charge of the XRD and AUC facility at ILS, he actively takes part in lab research projects too.


20210303_173843manoj-3

Manoj Kumar Barik

  • DMLT from JRN Rajasthan Vidyapeeth University, 2019.
  • Lab Technician in a Pvt diagnostic laboratory, Bhubaneswar, 2019-2021.
  • Trainee Lab Technician from March to December 2021 in our group.
  • Joined ILS as a Lab Technician from January 2022.

Manoj worked in our lab as a Trainee Lab Technician under the institutional Skill Development Technician Training Program for ten months and then joined in as a Lab Technician from January 2022. He is very much involved with the lab chores and helps other lab members with their laboratory experiments on a routine basis.


1

Dileep Vasudevan

  • BFSc (Fisheries), College of Fisheries, Cochin, (KAU, Thrissur), 1999.
  • MFSc (Microbiology), College of Fisheries, Mangalore (UAS, Bangalore), 2001.
  • PhD (Protein Crystallography), DBS, NUS, Singapore, 2007.
  • Post-doc (Chromatin Structural Biology), SBS, NTU, Singapore, 2006-2011
  • Post-doc (Infectious Disease Biology), Novartis Institute, Singapore, 2011-2012.
  • Joined ILS as a faculty in December 2012.

At some point in his life, Dileep was keen to do a PhD in Microbiology but was carried away by the charm of Protein Crystallography and jumped in. Dileep did his PhD at the Department of Biological Sciences, National University of Singapore (NUS) under the guidance of Dr. Swaminathan K. His first postdoc was with Dr. Curt Davey Alexander at the School of Biological Sciences, Nanyang Technological University (NTU), Singapore, and second postdoc from Novartis Institute for Tropical Diseases (NITD), Singapore with Dr. Christian Noble. As a Fisheries undergrad and a Microbiology postgraduate, he never liked Biochemistry and Physics, and had not even heard of crystallography! Ask him and he will explain how as a new student at NUS, his Ph.D. mentor Dr. Swami saw him totally lost in the department corridor and suggested a lab-rotation with his group. Little did he know about the field he is getting himself into. Long story made short, he stayed on in crystallography since then and at ILS he is heading a lab that claims to do Biophysics, Biochemistry & Crystallography!